Pharmaceutical Pellets and Granules – Manufacturing Plant Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities, Cost And Rev

Description:

The word “Pellet” has been usedto describe a variety of systematically produced, geometrically definedagglomerates obtained from diverse starting materials utilizing differentprocessing conditions. Pellets range in size, typically, between 0.5 – 1.5 mm,though other sizes could be prepared. Pellets are for pharmaceutical purposesand are produced primarily for the purpose of oral controlled-release dosageforms having gastro resistant or sustained-release properties or the capabilityof site-specific drug delivery. For such purposes, coated pellets areadministered in the form of hard gelatin capsules or disintegrating tabletsthat quickly liberate their contents of pellets in the stomach. Asdrug-delivery systems become more sophisticated, the role of pellets in thedesign and development of dosage forms is increasing. Formulation of drugs inmultiple-unit dosage forms, such as coated pellets filled in capsules orcompressed into tablets, offers flexibility as to target-release properties.The safety and efficacy of the formulation is higher than that of other dosageforms. Solid dosage formulation and design usually involves a serious of compromises,since producing the desired properties frequently involves competingobjectives. The correct selection and balance of excipients materials andprocesses in a solid dosage formulation, to achieve the desired response is notin practice easy to achieve. Pellets are of a great interest to thepharmaceutical industry for a variety of reasons. Palletized products not onlyoffer flexibility in dosage form design and development, but are also utilizedto improve the safety and efficiency of bioactive agents. Pellets range insize, between 0.5 to 1.5.

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