Dextrose is a carbohydrate caloric agent. Glucose, also known as dextrose, is a simple sugar that can be found in nature and are chemically identical. Dextrose is simply in lay terms sugar water and is generally used in those patients who have a very low blood glucose level or are unable to eat for some reason. It is a short term treatment generally. D5NS (Dextrose 5% in normal saline) is hypertonic, meaning it has a higher solute concentration than tissues, so it can be used to help draw fluids out of oedematous (fluid-swollen) tissues. Dextrose (glucose) 5% and normal saline (sodium chloride or common table salt 8.5 grams per 100 ml of distilled water), have the same tonicity or concentration of the rest of the body fluids, that is, they will do no harm to the rest of the fluids of the body whereas Saline or 9%NS IV solution is used as the universal fluid replacement in dehydrated individuals, it is the same composition as the body's normal fluid and most IV medications can safely be mixed with or push through saline. Dosage of dextrose depends on the age, weight, clinical condition, and fluid, electrolyte, and acid-base balance of the patient. Dextrose is readily metabolized; it increases blood glucose concentrations and provides calories. Dextrose may decrease body protein and nitrogen losses, promote glycogen deposition, and decrease or prevent ketosis if sufficient doses are given. Since dextrose is usually metabolized to carbon dioxide and water, administration of a solution of dextrose and water is equivalent to providing the same volume of free water. Following oral administration, dextrose, a monosaccharide, is rapidly absorbed from the small intestine principally by an active mechanism. In patients with hypoglycemia, increases in blood glucose concentration usually occur within 10â€“20 minutes and peak at about 40 minutes after oral administration of dextrose. In medicine, saline (also saline solution) is a general term referring to a sterile solution of sodium chloride (NaCl, more commonly known as salt) in water but is only sterile when it is to be placed intravenously; otherwise, a saline solution is a salt water solution. Thus, an intravenous infusion, a saline solution is typically mixed with dextrose or glucose to reduce any complications from infusing saline solution and to reduce the amount of sodium circulating through the blood stream. This works particularly well as a water and nutrient supplement to sustain hospitalized patients who are unable to eat or drink or who have suffered dehydration from severe vomiting or diarrhea. In present era, people are becoming very health conscious as the infection through air, water, food is prevailing across the country to the maximum. As hospitals are increasing day by day, doctors also prefer to use distilled water ampoules. There are several in organized and private sectors are engaged in the manufacturing of different grade dextrose saline solution. The demand growth is about 5% in each and every year. The entire demand gap is fulfilled by the domestic manufacturers. There is scope of dextrose saline bottle. New entrepreneur may launch in this field will be successful. Few Indian Major Players are as under: Gulshan Polyols Ltd. Kamala Sugar Mills Ltd. Origin Agrostar Ltd. Rai Agro Inds. Ltd. Sanjeevanee Pharmaceuticals Ltd. Santosh Starch Ltd. Sukhjit Starch & Chemicals Ltd. Unique Sugars Ltd. Universal Starch-Chem Allied Ltd.