Paracetamol

Description:

Paracetemol is an important intermediate in the manufacture of other pharmaceuticals like the antimalarial amodiaquine. Two types of paracetamol are commercially produced, namely powder and granules. The granules grade is called direct compressible product which is easier to use for making tablets. Three of the major manufacturers are in Andhra Pradesh? Srikrishna Pharma, Triton Laboratories and Srinivasa Agro industries and drug. The annual domestic requirement of paracetamol powder is about 10,000 tonnes. The total production is put at about 13,000 tonnes with the balance being exported. Paracetamol bulk drug project is considered as an ideal investment opportunity in small scale sector. There is good scope for new investment.

Paracetamol

Description:

The development in pharmaceutical industry is very rapid and continuous research work throughout the world has resulted in a number of new medicines. Paracetamol which is also known as acetaminophen, has been developed to be used in place of phenacetin as phenacetin has been found harmful to kidney. It is used mainly as a pain relieving compound and relieves pain of headaches and other pains arising from muscles and joints etc. The other uses are paracetamol is an intermediate in the manufacture of other pharmaceuticals like the antimalarial anidequien. The production of drugs and pharmaceuticals continued to show an increasing trend. The present production covers a wide range of bulk drugs including antibiotics, vitamins, hormones, sulpha drugs and a host of other synthetic, physiochemical and biological products. A number of drugs have been put under the scheme of delicensing to facilitate their production in the country in required quantities. Few new entrepreneurs can venture into this project.

Paracetamol

Description:

Paracetamol, also known as acetaminophen or APAP, is a medication used to treat pain and fever. It is typically used for mild to moderate pain. It is often sold in combination with other ingredients such as in many cold medications. In combination with opioid pain medication, paracetamol is used for more severe pain such as cancer pain and after surgery. It is typically used either by mouth or rectally but is also available intravenously. Effects last between two and four hours.

Paracetamol lacks anti-inflammatory action in rheumatic disorders. However, it is less toxic than the Aspirin and does not produce anemia and liver damage, which sometimes result from the continued use of acetanilide andacetophenetidin. It is also an important intermediate in the manufacture of other pharmaceuticals like theantimalarial amodiaquine.

The pharmaceutical industry in India ranks 3rd in the world terms of volume and 14th in terms of value. 20% of global exports in generics, making it the largest provider of generic medicines globally. USD 45 Billion in revenue by 2020, revenue of USD 55 billion by 2020 as base case, and can grow to USD 70 billion in a aggressive case scenario. USD 26.1 Billion in generics by 2016. USD 200 Billion to be spent on infrastructure by 2024. 

Global pharma companies are increasingly exploring low cost option to outsource research and manufacturing, because of emerging slow-down in patented drug sales and high cost of R&D.Thus, as an entrepreneur this project offers an exciting opportunity to you.

 

Few Indian Major Players are as under

• Ranbaxy (Daichi)

• Dr. Reddy's Labs

• Cipla

• Lupin

• AurobindoPharma

• Sun Pharma

• GlaxoSmithkline

• CadilaPharma

• Nicholas Piramal

• WokhardtLifesciences

Paracetamol

Description:

Paracetamol, also known as acetaminophen or APAP, is a medication used to treat pain and fever. It is typically used for mild to moderate pain. It is often sold in combination with other ingredients such as in many cold medications. In combination with opioid pain medication, paracetamol is used for more severe pain such as cancer pain and after surgery. It is typically used either by mouth or rectally but is also available intravenously. Effects last between two and four hours.

Paracetamol lacks anti-inflammatory action in rheumatic disorders. However, it is less toxic than the Aspirin and does not produce anemia and liver damage, which sometimes result from the continued use of acetanilide and acetophenotidine. It is also an important intermediate in the manufacture of other pharmaceuticals like theantimalarialamodiaquine.

The pharmaceutical industry in India ranks 3rd in the world terms of volume and 14th in terms of value. 20% of global exports in generics, making it the largest provider of generic medicines globally. USD 45 Billion in revenue by 2020, revenue of USD 55 billion by 2020 as base case, and can grow to USD 70 billion in a aggressive case scenario. USD 26.1 Billion in generics by 2016. USD 200 Billion to be spent on infrastructure by 2024. 

Global pharma companies are increasingly exploring low cost option to outsource research and manufacturing, because of emerging slow-down in patented drug sales and high cost of R&D.Any entrepreneur venture into this field will be successful. 

Paracetamol

Description:

 

Paracetamol (an international name used in Europe) and acetaminophen (an international name used in the USA) are two official names of the same chemical compound derived from its chemical name: N-acetyl-para-aminophenol (the segment ‘’CET’’ inserted between “para’’ and ‘’amino’’) and Acetyl-para-aminophenol. This drug has a long history and, as it often happens with important discoveries, it was found by chance. India enjoys an important position in the global pharmaceuticals sector. The country also has a large pool of scientists and engineers with a potential to steer the industry ahead to greater heights. Presently, over 80% of the antiretroviral drugs used globally to combat AIDS (Acquired Immune Deficiency Syndrome) are supplied by Indian pharmaceutical firms. The pharmaceutical industry in India ranks 3rd in the world terms of volume and 14^th in terms of value. 20% of global exports in generics, making it the largest provider of generic medicines globally.

Paracetamol is a well-established treatment, recommended by healthcare organizations globally, for fever reduction and mild to moderate pain relief in adults and children aged two months and over.1 Paracetamol has been available for more than 60 years and is used by millions of patients worldwide. Paracetamol is currently recommended by public health authorities, including the World Health Organization (WHO), as part of symptomatic treatment to relieve mild to moderate pain and reduce fever in COVID-19.

·         Headache Swiss: Austrian and German headache societies state that Paracetamol with caffeine is also used in Headache. In India paracetamol is also prescribed to relieve headache. Paracetamol is also used to relieve migraine in some countries.

·         Toothache: Some studies show that paracetamol is also used in pain of tooth.

·         Menstrual Period Pain: Paracetamol is often prescribe with Dicyclomine Hydrochloride or Mefenamic Acid to relieve pain during menstrual period. 

Tablet segment holds the major share of the market as it is most commonly used form of paracetamol. Huge amounts of paracetamol are used to treat pain. According to University of Oxford, an estimate of the amount of paracetamol sold is just under 6,300 tonnes a year in the United Kingdom. That is 35 tonnes per million of population, 35 grams or 70 paracetamol tablets each, every year.

India’s domestic pharmaceutical market turnover reached Rs 1.4 lakh crore (US$ 20.03 billion) in 2019, up 9.8% y-o-y from Rs 129,015 crore (US$ 18.12 billion) in 2018. The Indian pharmaceutical industry is the third largest in the world in terms of volume of output and thirteenth in domestic demand. However, the Indian industry, valued at USD 17 bn in represented just over 1% of the global pharmaceutical industry (USD 1700 bn) in value terms. The domestic market is estimated at Rs. 680 bn. India has the world's third largest active pharmaceutical ingredients (API) for the industry valued at a little less than USD 2 bn. Top 5 API producers account for approximately 6.5 %. The leading APIs are anti-infective, gastrointestinal, cardiovascular and respiratory drugs. As a whole there is a good scope for new entrepreneur to invest in this business.

Few Indian major players

1.   Alpha Remedies Ltd.

2.   Alta Laboratories Ltd.

3.   Farmson Pharmaceutical Gujarat Pvt. Ltd.

4.   Granules India Ltd.

5.   Haffkine Ajintha Pharmaceuticals Ltd.

6.   Nalin Chemicals Ltd.